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News and developments from Affinia Therapeutics

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Press Release - Oct 24, 2023

Affinia Therapeutics to Present Preclinical Data on Novel AAV Capsids at the 30th European Society of Gene and Cell Therapy 2023 Annual Congress

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ASGCT 2023 Oral Presentation - May 18, 2023

Structure-activity relationships guided engineering of AAV capsids with optimized skeletal muscle, cardiac muscle, and CNS tropism.

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ASGCT 2023 Poster Presentation - May 18, 2023

Improvement of Yield and Critical Quality Attributes Through Process Development of a Novel Adeno-Associated Viral Vector Capsid (Anc80L65)

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ASGCT 2023 Poster Presentation - May 17, 2023

Limitations of Marmosets as an Animal Model for AAV Mediated Liver Gene Transfer.

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Press Release - May 18, 2023

Affinia Therapeutics Presents New Preclinical Data on Novel AAV Capsids for Skeletal Muscle, Cardiac Muscle, and CNS at the American Society of Gene & Cell Therapy 26TH Annual Meeting

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Press Release - May 3, 2023

Affinia Therapeutics to Present New Data at the American Society of Gene and Cell Therapy Annual Meeting

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Presentation - May 16, 2022

Pretreatment with IVIG reduces peripheral transduction of AAV9 delivered to the CNS

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Press Release – May 16, 2022

Affinia Therapeutics Presents New Data at American Society of Gene and Cell Therapy Annual Meeting

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Press Release – March 8, 2022

Affinia Therapeutics Strengthens Leadership Team with Appointment of Diana M. Brainard, M.D., to the Board of Directors

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Press Release – December 14, 2021

Affinia Therapeutics Appoints Thomas Leggett as Chief Financial Officer

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Press Release – October 6, 2021

Affinia Therapeutics Appoints Carole Faig to Board of Directors

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Press Release – September 8, 2021

Affinia Therapeutics Announces Indications for Lead Gene Therapy Programs to Advance the Treatment of Neurologic and Neuro-oncologic Diseases supported by Multi-Year Manufacturing Agreement with Lonza Group

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Press Release – July 20, 2021

Affinia Therapeutics Announces Collaboration with the Institute of Molecular and Clinical Ophthalmology Basel (IOB) To Rationally Design Novel CNS Promoters for Gene Therapy

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Presentation – May 13, 2021

AAVX Resin Binding Site Identification Via Library Screening Analysis on Novel AAV Vectors

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Presentation – May 11, 2021

AAVmod2, an AAV Capsid Engineered to Independently Detarget the Liver and Enhance Gene Delivery to Skeletal Muscle

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Presentation – May 11, 2021

CSF delivery of Anc80L65 in the non-human primate brain results in widespread gene transfer throughout the central nervous system compared to AAV9

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Press Release – May 13, 2021

Affinia Therapeutics Presents New Data and Updates on AAV Platform at American Society of Gene and Cell Therapy Annual Meeting

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Press Release – May 3, 2021

Affinia Therapeutics Closes $110 Million Series B Financing

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Press Release – April 27, 2021

Affinia Therapeutics to Present New Data and Updates on AAV Platform at the American Society of Gene and Cell Therapy Annual Meeting

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Press Release – February 17, 2021

Affinia Therapeutics Announces Addition of Gene Therapy Scientific and Medical Experts to Leadership Team to Advance Novel Gene Therapy Platform and Programs to the Clinic

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Press Release – June 8, 2020

Affinia Therapeutics Announces Appointment of Elliott Sigal, M.D., Ph.D. to the Company’s Board of Directors

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Press Release – April 27 2020

Vertex Pharmaceuticals and Affinia Therapeutics Establish Multi-Year Collaboration to Discover and Develop Novel AAV Capsids for Genetic Therapies

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Press Release – March 31, 2020

Affinia Therapeutics Raises $60M in Series A Financing to Advance Rational Design AAV Platform and Transformative Gene Therapies

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Publication – Jul 8, 2019

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

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Publication – Jul 23, 2018

Efficient gene transfer to the central nervous system by single-stranded Anc80L65

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Publication – Aug 11, 2015

In silico reconstruction of the viral evolutionary lineage yields a potent gene therapy vector

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